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An atomic model of brome mosaic virus using direct electron detection and real-space optimization
Advances in electron cryo-microscopy have enabled structure determination of macromolecules at near-atomic resolution. However, structure determination, even using de novo methods, remains susceptible to model bias and overfitting. Here we describe a complete workflow for data acquisition, image pro...
Autores principales: | Wang, Zhao, Hryc, Corey F., Bammes, Benjamin, Afonine, Pavel V., Jakana, Joanita, Chen, Dong-Hua, Liu, Xiangan, Baker, Matthew L., Kao, Cheng, Ludtke, Steven J., Schmid, Michael F., Adams, Paul D., Chiu, Wah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155512/ https://www.ncbi.nlm.nih.gov/pubmed/25185801 http://dx.doi.org/10.1038/ncomms5808 |
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