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Chronic myeloid leukemia with an e1a3 BCR-ABL fusion protein: transformation to lymphoid blast crisis

Chronic myelogenous leukemia (CML) results from the neoplastic transformation of a hematopoietic stem cell. CML is cytogenetically characterized by the presence of the Philadelphia chromosome (Ph’). Most patients with CML express e13a2 or e14a2 mRNAs that result from a rearrangement of the major bre...

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Detalles Bibliográficos
Autores principales: Martinez-Serra, Jordi, del Campo, Raquel, Gutierrez, Antonio, Antich, Jose Luis, Ginard, Magdalena, Durán, Maria A, Bento, Leyre, Ros, Teresa, Amat, Juan C, Vidal, Carmen, Iglesias, Julio F, Orlinska, Izabela, Besalduch, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155769/
https://www.ncbi.nlm.nih.gov/pubmed/25197554
http://dx.doi.org/10.1186/2050-7771-2-14