TLR2 Signaling is Required for the Innate, but Not Adaptive Response to LVS clpB

Toll-like receptor 2 (TLR2) is the best-characterized pattern-recognition receptor for the highly pathogenic intracellular bacterium, Francisella tularensis. We previously identified a mutant in the live vaccine strain (LVS) of Francisella, LVS clpB, which is attenuated, but induces a protective imm...

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Detalles Bibliográficos
Autores principales: Roberts, Lydia M., Ledvina, Hannah E., Sempowski, Gregory D., Frelinger, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155801/
https://www.ncbi.nlm.nih.gov/pubmed/25250027
http://dx.doi.org/10.3389/fimmu.2014.00426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155801/
https://www.ncbi.nlm.nih.gov/pubmed/25250027
http://dx.doi.org/10.3389/fimmu.2014.00426

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