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TLR2 Signaling is Required for the Innate, but Not Adaptive Response to LVS clpB
Toll-like receptor 2 (TLR2) is the best-characterized pattern-recognition receptor for the highly pathogenic intracellular bacterium, Francisella tularensis. We previously identified a mutant in the live vaccine strain (LVS) of Francisella, LVS clpB, which is attenuated, but induces a protective imm...
Autores principales: | Roberts, Lydia M., Ledvina, Hannah E., Sempowski, Gregory D., Frelinger, Jeffrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155801/ https://www.ncbi.nlm.nih.gov/pubmed/25250027 http://dx.doi.org/10.3389/fimmu.2014.00426 |
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