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Tissue distribution of residual antimony in rats treated with multiple doses of meglumine antimoniate

Meglumine antimoniate (MA) and sodium stibogluconate are pentavalent antimony (Sb(V)) drugs used since the mid-1940s. Notwithstanding the fact that they are first-choice drugs for the treatment of leishmaniases, there are gaps in our knowledge of their toxicological profile, mode of action and kinet...

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Detalles Bibliográficos
Autores principales: Coelho, Deise Riba, Miranda, Elaine Silva, Saint’Pierre, Tatiana Dillenburg, Paumgartten, Francisco José Roma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155842/
https://www.ncbi.nlm.nih.gov/pubmed/25075781
http://dx.doi.org/10.1590/0074-0276140030