Cargando…
Nigrostriatal dynein changes in A53T alpha-synuclein transgenic mice
The accumulation of misfolded a-synuclein is mechanistically linked to neurodegeneration in Parkinson’s disease (PD) and other alpha-synucleinopathies. However, how alpha-synuclein causes neurodegeneration is unresolved. Several studies have supported the involvement of dynein, the major motor for r...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156029/ https://www.ncbi.nlm.nih.gov/pubmed/25210616 http://dx.doi.org/10.12688/f1000research.3507.1 |