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Nigrostriatal dynein changes in A53T alpha-synuclein transgenic mice

The accumulation of misfolded a-synuclein is mechanistically linked to neurodegeneration in Parkinson’s disease (PD) and other alpha-synucleinopathies. However, how alpha-synuclein causes neurodegeneration is unresolved. Several studies have supported the involvement of dynein, the major motor for r...

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Detalles Bibliográficos
Autores principales:	Liu, Yan, Yuan, Yu-He, Sun, Jian-Dong, Li, Jing, Li, Zhi-Peng, Chen, Nai-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156029/ https://www.ncbi.nlm.nih.gov/pubmed/25210616 http://dx.doi.org/10.12688/f1000research.3507.1

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