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A tale of two trials: The impact of 5α-reductase inhibition on prostate cancer (Review)

The use of 5α-reductase inhibitors (5α-RIs) as prostate cancer chemoprevention agents is controversial. Two large randomized trials, the Prostate Cancer Prevention Trial (PCPT) and the Reduction by Dutasteride of Prostate Cancer Events (REDUCE) Trial, have both shown a decreased incidence of prostat...

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Detalles Bibliográficos
Autores principales: LACY, JOHN M., KYPRIANOU, NATASHA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156162/
https://www.ncbi.nlm.nih.gov/pubmed/25202340
http://dx.doi.org/10.3892/ol.2014.2388