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Concomitant depletion of PTEN and p27 and overexpression of cyclin D1 may predict a worse prognosis for patients with post-operative stage II and III colorectal cancer

Prognostic markers for colorectal cancer (CRC) have not yet been fully investigated. Phosphatase and tensin homolog (PTEN), p27 and Cyclin D1 play significant roles in tumorigenesis and cell cycle regulation, and therefore require evaluation for their prognostic value in this disease. The aim of the...

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Detalles Bibliográficos
Autores principales: LI, JING, YIN, LIN-LIN, SU, KE-LI, ZHANG, GANG-FENG, WANG, JING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156215/
https://www.ncbi.nlm.nih.gov/pubmed/25202365
http://dx.doi.org/10.3892/ol.2014.2350