Glycosylation and Disulfide Bond Analysis of Transiently and Stably Expressed Clade C HIV-1 gp140 Trimers in 293T Cells Identifies Disulfide Heterogeneity Present in Both Proteins and Differences in O-Linked Glycosylation

[Image: see text] The HIV-1 envelope protein (Env) mediates viral entry into host cells to initiate infection and is the sole target of antibody-based vaccine development. Significant efforts have been made toward the design, engineering, and expression of various soluble forms of HIV Env immunogen,...

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Detalles Bibliográficos
Autores principales: Go, Eden P., Hua, David, Desaire, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156237/
https://www.ncbi.nlm.nih.gov/pubmed/25026075
http://dx.doi.org/10.1021/pr5003643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156237/
https://www.ncbi.nlm.nih.gov/pubmed/25026075
http://dx.doi.org/10.1021/pr5003643

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