Cargando…

A General Diastereoselective Catalytic Vinylogous Aldol Reaction Among Tetramic Acid-Derived Pyrroles

[Image: see text] A catalytic diastereoselective aldol reaction has been developed for N1-arylated/C2-O-silylated/C3-methylated and brominated/C4-O-methylated pyrroles in its reactions with various aldehydes. Syn adducts emerge with regard to the vicinal nitrogen and oxygen heteroatom substituents....

Descripción completa

Detalles Bibliográficos
Autores principales: David, Jonathan G., Bai, Wen-Ju, Weaver, Marisa G., Pettus, Thomas R. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156244/
https://www.ncbi.nlm.nih.gov/pubmed/25119431
http://dx.doi.org/10.1021/ol501715r