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A Lewis Acid Catalyzed Annulation to 2,1-Benzisoxazoles

[Image: see text] We report here a new, atom economical annulation to 2,1-benzisoxazole scaffolds via the BF(3)·Et(2)O-catalyzed reaction of glyoxylate esters and nitrosoarenes. The developed method represents a convergent route to this compound class from previously unexplored inputs and provides a...

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Detalles Bibliográficos
Autores principales: Otley, Kate D., Ellman, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156248/
https://www.ncbi.nlm.nih.gov/pubmed/25157596
http://dx.doi.org/10.1021/jo5015432