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Utility of RNA-seq and GPMDB Protein Observation Frequency for Improving the Sensitivity of Protein Identification by Tandem MS

[Image: see text] Tandem mass spectrometry (MS/MS) followed by database search is the method of choice for protein identification in proteomic studies. Database searching methods employ spectral matching algorithms and statistical models to identify and quantify proteins in a sample. In general, the...

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Detalles Bibliográficos
Autores principales: Shanmugam, Avinash K., Yocum, Anastasia K., Nesvizhskii, Alexey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156250/
https://www.ncbi.nlm.nih.gov/pubmed/25026199
http://dx.doi.org/10.1021/pr500496p