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Highly Selective Palladium-Catalyzed Cross-Coupling of Secondary Alkylzinc Reagents with Heteroaryl Halides

[Image: see text] The highly selective palladium-catalyzed Negishi coupling of secondary alkylzinc reagents with heteroaryl halides is described. The development of a series of biarylphosphine ligands has led to the identification of an improved catalyst for the coupling of electron-deficient hetero...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Niedermann, Katrin, Han, Chong, Buchwald, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156254/
https://www.ncbi.nlm.nih.gov/pubmed/25153332
http://dx.doi.org/10.1021/ol502230p