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Rice ORMDL Controls Sphingolipid Homeostasis Affecting Fertility Resulting from Abnormal Pollen Development

The orosomucoids (ORM) are ER-resisdent polypeptides encoded by ORM and ORMDL (ORM-like) genes. In humans, ORMDL3 was reported as genetic risk factor associated to asthma. In yeast, ORM proteins act as negative regulators of sphingolipid synthesis. Sphingolipids are important molecules regulating se...

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Detalles Bibliográficos
Autores principales: Chueasiri, Chutharat, Chunthong, Ketsuwan, Pitnjam, Keasinee, Chakhonkaen, Sriprapai, Sangarwut, Numphet, Sangsawang, Kanidta, Suksangpanomrung, Malinee, Michaelson, Louise V., Napier, Johnathan A., Muangprom, Amorntip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156325/
https://www.ncbi.nlm.nih.gov/pubmed/25192280
http://dx.doi.org/10.1371/journal.pone.0106386