Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells

Despite the fact that new treatment regimes have improved overall survival of patients challenged by colorectal cancer (CRC), prognosis in the metastatic situation is still restricted. The Bcl-2 family of proteins has been identified as promising anti cancer drug target. Even though small molecules...

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Detalles Bibliográficos
Autores principales: Koehler, Bruno Christian, Scherr, Anna-Lena, Lorenz, Stephan, Elssner, Christin, Kautz, Nicole, Welte, Stefan, Jaeger, Dirk, Urbanik, Toni, Schulze-Bergkamen, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156353/
https://www.ncbi.nlm.nih.gov/pubmed/25192188
http://dx.doi.org/10.1371/journal.pone.0106571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156353/
https://www.ncbi.nlm.nih.gov/pubmed/25192188
http://dx.doi.org/10.1371/journal.pone.0106571

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