The Protective Role of Fucosylated Chondroitin Sulfate, a Distinct Glycosaminoglycan, in a Murine Model of Streptozotocin-Induced Diabetic Nephropathy

BACKGROUND: Heparanase-1 activation, albuminuria, and a decrease in glomerular heparan sulfate (HS) have been described in diabetic nephropathy (DN). Glycosaminoglycan (GAG)-based drugs have been shown to have renoprotective effects in this setting, although recent trials have questioned their clini...

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Detalles Bibliográficos
Autores principales: Gomes, Conrado L. R., Leão, Cristina L., Venturotti, Carolina, Barreira, André L., Guimarães, Gabriela, Fonseca, Roberto J. C., Fortunato, Rodrigo S., Mourão, Paulo A. S., Delgado, Alvimar G., Takiya, Christina M., Leite, Maurilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156394/
https://www.ncbi.nlm.nih.gov/pubmed/25192337
http://dx.doi.org/10.1371/journal.pone.0106929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156394/
https://www.ncbi.nlm.nih.gov/pubmed/25192337
http://dx.doi.org/10.1371/journal.pone.0106929

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