Transcriptome Profiling of Spinal Muscular Atrophy Motor Neurons Derived from Mouse Embryonic Stem Cells

Proximal spinal muscular atrophy (SMA) is an early onset, autosomal recessive motor neuron disease caused by loss of or mutation in SMN1 (survival motor neuron 1). Despite understanding the genetic basis underlying this disease, it is still not known why motor neurons (MNs) are selectively affected...

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Detalles Bibliográficos
Autores principales: Maeda, Miho, Harris, Ashlee W., Kingham, Brewster F., Lumpkin, Casey J., Opdenaker, Lynn M., McCahan, Suzanne M., Wang, Wenlan, Butchbach, Matthew E. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156416/
https://www.ncbi.nlm.nih.gov/pubmed/25191843
http://dx.doi.org/10.1371/journal.pone.0106818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156416/
https://www.ncbi.nlm.nih.gov/pubmed/25191843
http://dx.doi.org/10.1371/journal.pone.0106818

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