Evaluation of Antithrombotic Activity of Thrombin DNA Aptamers by a Murine Thrombosis Model

Aptamers are nucleic acid based molecular recognition elements with a high potential for the theranostics. Some of the aptamers are under development for therapeutic applications as promising antithrombotic agents; and G-quadruplex DNA aptamers, which directly inhibit the thrombin activity, are amon...

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Detalles Bibliográficos
Autores principales: Zavyalova, Elena, Samoylenkova, Nadezhda, Revishchin, Alexander, Golovin, Andrey, Pavlova, Galina, Kopylov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156426/
https://www.ncbi.nlm.nih.gov/pubmed/25192011
http://dx.doi.org/10.1371/journal.pone.0107113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156426/
https://www.ncbi.nlm.nih.gov/pubmed/25192011
http://dx.doi.org/10.1371/journal.pone.0107113

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