Lymph-borne CD8α(+) dendritic cells are uniquely able to cross-prime CD8(+) T cells with antigen acquired from intestinal epithelial cells

Cross-presentation of cellular antigens is crucial for priming CD8(+) T cells, and generating immunity to intracellular pathogens—particularly viruses. It is unclear which intestinal phagocytes perform this function in vivo. To address this, we examined dendritic cells (DCs) from the intestinal lymp...

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Detalles Bibliográficos
Autores principales: Cerovic, V, Houston, S A, Westlund, J, Utriainen, L, Davison, E S, Scott, C L, Bain, C C, Joeris, T, Agace, W W, Kroczek, R A, Mowat, A M, Yrlid, U, Milling, S WF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156465/
https://www.ncbi.nlm.nih.gov/pubmed/24850430
http://dx.doi.org/10.1038/mi.2014.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156465/
https://www.ncbi.nlm.nih.gov/pubmed/24850430
http://dx.doi.org/10.1038/mi.2014.40

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