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Lymph-borne CD8α(+) dendritic cells are uniquely able to cross-prime CD8(+) T cells with antigen acquired from intestinal epithelial cells
Cross-presentation of cellular antigens is crucial for priming CD8(+) T cells, and generating immunity to intracellular pathogens—particularly viruses. It is unclear which intestinal phagocytes perform this function in vivo. To address this, we examined dendritic cells (DCs) from the intestinal lymp...
Autores principales: | Cerovic, V, Houston, S A, Westlund, J, Utriainen, L, Davison, E S, Scott, C L, Bain, C C, Joeris, T, Agace, W W, Kroczek, R A, Mowat, A M, Yrlid, U, Milling, S WF |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156465/ https://www.ncbi.nlm.nih.gov/pubmed/24850430 http://dx.doi.org/10.1038/mi.2014.40 |
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