Tracking of the dynamic localization of the Rab-specific HOPS subunits reveal their distinct interaction with Ypt7 and vacuoles

Endosomal and vacuole fusion depends on the two homologous tethering complexes CORVET and HOPS. HOPS binds the activated Rab GTPase Ypt7 via two distinct subunits, Vps39 and Vps41. To understand the participation and possible polarity of Vps41 and Vps39 during tethering, we used an in vivo approach....

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Detalles Bibliográficos
Autores principales: Auffarth, Kathrin, Arlt, Henning, Lachmann, Jens, Cabrera, Margarita, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156483/
https://www.ncbi.nlm.nih.gov/pubmed/25210650
http://dx.doi.org/10.4161/cl.29191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156483/
https://www.ncbi.nlm.nih.gov/pubmed/25210650
http://dx.doi.org/10.4161/cl.29191

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