The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer

Introduction The RNA-binding protein hnRNPA2 (HNRNPA2B1) is upregulated in cancer, where it controls alternative pre-mRNA splicing of cancer-relevant genes. Cytoplasmic hnRNPA2 is reported in aggressive cancers, but is functionally uncharacterized. We explored the role of hnRNPA2 in prostate cancer...

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Detalles Bibliográficos
Autores principales: Stockley, Jacqueline, Villasevil, M Eugenia M, Nixon, Colin, Ahmad, Imran, Leung, Hing Y, Rajan, Prabhakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156506/
https://www.ncbi.nlm.nih.gov/pubmed/24823909
http://dx.doi.org/10.4161/rna.28800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156506/
https://www.ncbi.nlm.nih.gov/pubmed/24823909
http://dx.doi.org/10.4161/rna.28800

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