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Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson’s disease by laser ablation inductively coupled plasma mass spectrometry

BACKGROUND: Neuropsychiatric affection involving extrapyramidal symptoms is a frequent component of Wilson’s disease (WD). WD is caused by a genetic defect of the copper (Cu) efflux pump ATPase7B. Mouse strains with natural or engineered transgenic defects of the Atp7b gene have served as model of W...

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Detalles Bibliográficos
Autores principales: Boaru, Sorina Georgiana, Merle, Uta, Uerlings, Ricarda, Zimmermann, Astrid, Weiskirchen, Sabine, Matusch, Andreas, Stremmel, Wolfgang, Weiskirchen, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156608/
https://www.ncbi.nlm.nih.gov/pubmed/25142911
http://dx.doi.org/10.1186/1471-2202-15-98