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Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson’s disease by laser ablation inductively coupled plasma mass spectrometry
BACKGROUND: Neuropsychiatric affection involving extrapyramidal symptoms is a frequent component of Wilson’s disease (WD). WD is caused by a genetic defect of the copper (Cu) efflux pump ATPase7B. Mouse strains with natural or engineered transgenic defects of the Atp7b gene have served as model of W...
Autores principales: | Boaru, Sorina Georgiana, Merle, Uta, Uerlings, Ricarda, Zimmermann, Astrid, Weiskirchen, Sabine, Matusch, Andreas, Stremmel, Wolfgang, Weiskirchen, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156608/ https://www.ncbi.nlm.nih.gov/pubmed/25142911 http://dx.doi.org/10.1186/1471-2202-15-98 |
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