Epac, Rap and Rab3 act in concert to mobilize calcium from sperm’s acrosome during exocytosis

BACKGROUND: Exocytosis of sperm’s single secretory granule or acrosome (acrosome reaction, AR) is a highly regulated event essential for fertilization. The AR begins with an influx of calcium from the extracellular milieu and continues with the synthesis of cAMP and the activation of its target Epac...

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Detalles Bibliográficos
Autores principales: Ruete, María C, Lucchesi, Ornella, Bustos, Matías A, Tomes, Claudia N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156617/
https://www.ncbi.nlm.nih.gov/pubmed/25159528
http://dx.doi.org/10.1186/s12964-014-0043-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156617/
https://www.ncbi.nlm.nih.gov/pubmed/25159528
http://dx.doi.org/10.1186/s12964-014-0043-0

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