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Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs
The central memory T cell (TCM) model forms a unique HIV-1 latency model based on primary cells that closely resemble in vivo TCM. The virus employed in this model is based on an engineered vector incapable of replication after initial infection. We show that despite this strategy, replication compe...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156640/ https://www.ncbi.nlm.nih.gov/pubmed/25142072 http://dx.doi.org/10.1186/s12977-014-0070-3 |