Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs

The central memory T cell (TCM) model forms a unique HIV-1 latency model based on primary cells that closely resemble in vivo TCM. The virus employed in this model is based on an engineered vector incapable of replication after initial infection. We show that despite this strategy, replication compe...

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Detalles Bibliográficos
Autores principales: Bonczkowski, Pawel, De Spiegelaere, Ward, Bosque, Alberto, White, Cory H, Van Nuffel, Anouk, Malatinkova, Eva, Kiselinova, Maja, Trypsteen, Wim, Witkowski, Wojciech, Vermeire, Jolien, Verhasselt, Bruno, Martins, Laura, Woelk, Christopher H, Planelles, Vicente, Vandekerckhove, Linos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156640/
https://www.ncbi.nlm.nih.gov/pubmed/25142072
http://dx.doi.org/10.1186/s12977-014-0070-3

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