GlialCAM, a CLC-2 Cl(-) Channel Subunit, Activates the Slow Gate of CLC Chloride Channels

GlialCAM, a glial cell adhesion molecule mutated in megalencephalic leukoencephalopathy with subcortical cysts, targets the CLC-2 Cl(-) channel to cell contacts in glia and activates CLC-2 currents in vitro and in vivo. We found that GlialCAM clusters all CLC channels at cell contacts in vitro and t...

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Detalles Bibliográficos
Autores principales: Jeworutzki, Elena, Lagostena, Laura, Elorza-Vidal, Xabier, López-Hernández, Tania, Estévez, Raúl, Pusch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2014
Materias:
Channels and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156679/
https://www.ncbi.nlm.nih.gov/pubmed/25185546
http://dx.doi.org/10.1016/j.bpj.2014.07.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156679/
https://www.ncbi.nlm.nih.gov/pubmed/25185546
http://dx.doi.org/10.1016/j.bpj.2014.07.040

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