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Recombinant TIMP-1-GPI inhibits growth of fibrosarcoma and enhances tumor sensitivity to doxorubicin

Fibrosarcomas show a high incidence of recurrence and general resistance to apoptosis. Limiting tumor regrowth and increasing their sensitivity to chemotherapy and apoptosis represent key issues in developing more effective treatments of these tumors. Tissue inhibitor of metalloproteinase 1 (TIMP-1)...

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Detalles Bibliográficos
Autores principales: Bao, Q., Niess, H., Djafarzadeh, R., Zhao, Y., Schwarz, B., Angele, M. K., Jauch, K.-W., Nelson, P. J., Bruns, C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156787/
https://www.ncbi.nlm.nih.gov/pubmed/23934106
http://dx.doi.org/10.1007/s11523-013-0294-5