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Fibril Elongation by Aβ(17–42): Kinetic Network Analysis of Hybrid-Resolution Molecular Dynamics Simulations
[Image: see text] A critical step of β-amyloid fibril formation is fibril elongation in which amyloid-β monomers undergo structural transitions to fibrillar structures upon their binding to fibril tips. The atomic detail of the structural transitions remains poorly understood. Computational characte...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156860/ https://www.ncbi.nlm.nih.gov/pubmed/25134066 http://dx.doi.org/10.1021/ja507002p |