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Z-Selective Olefin Metathesis on Peptides: Investigation of Side-Chain Influence, Preorganization, and Guidelines in Substrate Selection

[Image: see text] Olefin metathesis has emerged as a promising strategy for modulating the stability and activity of biologically relevant compounds; however, the ability to control olefin geometry in the product remains a challenge. Recent advances in the design of cyclometalated ruthenium catalyst...

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Detalles Bibliográficos
Autores principales: Mangold, Shane L., O’Leary, Daniel J., Grubbs, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156862/
https://www.ncbi.nlm.nih.gov/pubmed/25102124
http://dx.doi.org/10.1021/ja507166g