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A proton wire to couple aminoacyl-tRNA accommodation and peptide bond formation on the ribosome
During peptide bond formation on the ribosome the α-amine of an aminoacyl-tRNA attacks the ester carbonyl carbon of a peptidyl-tRNA to yield a peptide lengthened by one amino acid. Although the ribosome's contribution to catalysis is predominantly entropic, the lack of high-resolution structura...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156881/ https://www.ncbi.nlm.nih.gov/pubmed/25132179 http://dx.doi.org/10.1038/nsmb.2871 |