RNA polymerase pausing and nascent RNA structure formation are linked through clamp domain movement

The rates of RNA synthesis and nascent RNA folding into biologically active structures are linked via pausing by RNA polymerase (RNAP). Structures that form within the RNA exit channel can increase pausing by interacting with bacterial RNAP or decrease pausing by preventing backtracking. Conversely,...

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Detalles Bibliográficos
Autores principales: Hein, Pyae P., Kolb, Kellie E., Windgassen, Tricia, Bellecourt, Michael J., Darst, Seth A., Mooney, Rachel A., Landick, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156911/
https://www.ncbi.nlm.nih.gov/pubmed/25108353
http://dx.doi.org/10.1038/nsmb.2867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156911/
https://www.ncbi.nlm.nih.gov/pubmed/25108353
http://dx.doi.org/10.1038/nsmb.2867

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