Cargando…
RNA polymerase pausing and nascent RNA structure formation are linked through clamp domain movement
The rates of RNA synthesis and nascent RNA folding into biologically active structures are linked via pausing by RNA polymerase (RNAP). Structures that form within the RNA exit channel can increase pausing by interacting with bacterial RNAP or decrease pausing by preventing backtracking. Conversely,...
Autores principales: | Hein, Pyae P., Kolb, Kellie E., Windgassen, Tricia, Bellecourt, Michael J., Darst, Seth A., Mooney, Rachel A., Landick, Robert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156911/ https://www.ncbi.nlm.nih.gov/pubmed/25108353 http://dx.doi.org/10.1038/nsmb.2867 |
Ejemplares similares
-
Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase
por: Windgassen, Tricia A., et al.
Publicado: (2014) -
The bridge helix coordinates movements of modules in RNA polymerase
por: Hein, Pyae P, et al.
Publicado: (2010) -
The elemental mechanism of transcriptional pausing
por: Saba, Jason, et al.
Publicado: (2019) -
Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo
por: Imashimizu, Masahiko, et al.
Publicado: (2015) -
Erratum to: Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo
por: Imashimizu, Masahiko, et al.
Publicado: (2015)