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The Effects of Tamoxifen in Combination with Tranilast on CXCL12-CXCR4 Axis and Invasion in Breast Cancer Cell Lines

It has been reported that CXCL12 binding to CXCR4 induces several intracellular signaling pathways, and enhances survival, proliferation, and migration of malignant cells. In the present study, we examined the effects of anti-estrogen tamoxifen and anti-allergic tranilast drugs as a single or in com...

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Detalles Bibliográficos
Autores principales: Darakhshan, Sara, Bidmeshkipour, Ali, Mansouri, Kamran, Saeid, Hakhamaneshi Mohammad, Ghanbari, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157045/
https://www.ncbi.nlm.nih.gov/pubmed/25237365