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Endosomal acidification and cathepsin L activity is required for calicivirus replication

The role of cellular proteases and endosome maturation in the entry of caliciviruses including porcine enteric calicivirus (PEC), murine norovirus (MNV)-1 and feline calicivirus (FCV) were investigated. Treatment with chloroquine or cathepsin L inhibitors, but not cathepsin B inhibitors, significant...

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Detalles Bibliográficos
Autores principales: Shivanna, Vinay, Kim, Yunjeong, Chang, Kyeong-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157107/
https://www.ncbi.nlm.nih.gov/pubmed/25108379
http://dx.doi.org/10.1016/j.virol.2014.07.025