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Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex

The mammalian circadian clock is driven by a transcriptional–translational feedback loop, which produces robust 24-hr rhythms. Proper oscillation of the clock depends on the complex formation and periodic turnover of the Period and Cryptochrome proteins, which together inhibit their own transcriptio...

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Detalles Bibliográficos
Autores principales: Nangle, Shannon N, Rosensweig, Clark, Koike, Nobuya, Tei, Hajime, Takahashi, Joseph S, Green, Carla B, Zheng, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157330/
https://www.ncbi.nlm.nih.gov/pubmed/25127877
http://dx.doi.org/10.7554/eLife.03674