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Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex
The mammalian circadian clock is driven by a transcriptional–translational feedback loop, which produces robust 24-hr rhythms. Proper oscillation of the clock depends on the complex formation and periodic turnover of the Period and Cryptochrome proteins, which together inhibit their own transcriptio...
Autores principales: | Nangle, Shannon N, Rosensweig, Clark, Koike, Nobuya, Tei, Hajime, Takahashi, Joseph S, Green, Carla B, Zheng, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157330/ https://www.ncbi.nlm.nih.gov/pubmed/25127877 http://dx.doi.org/10.7554/eLife.03674 |
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