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Structural basis for the substrate selectivity of PvuRts1I, a 5-hydroxymethylcytosine DNA restriction endonuclease

5-Hydroxymethylation is a curious modification of cytosine that was discovered some decades ago, but its functional role in eukaryotes still awaits elucidation. 5-Hydroxymethyl­cytosine is an epigenetic marker that is crucial for multiple biological processes. The profile is altered under certain di...

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Detalles Bibliográficos
Autores principales: Shao, Chen, Wang, Chengliang, Zang, Jianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157451/
https://www.ncbi.nlm.nih.gov/pubmed/25195760
http://dx.doi.org/10.1107/S139900471401606X