Reciprocal modulation of Aβ42 aggregation by copper and homocysteine

Hyperhomocysteinemia is a risk factor for Alzheimer’s disease (AD). Both homocysteine (Hcy) and amyloid β (Aβ), which accumulates in the brain of AD patients, bind copper. Aim of this study was to test the hypothesis that the association of Hcy and AD results from a molecular interaction between Hcy...

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Detalles Bibliográficos
Autores principales: Keskitalo, Salla, Farkas, Melinda, Hanenberg, Michael, Szodorai, Anita, Kulic, Luka, Semmler, Alexander, Weller, Michael, Nitsch, Roger M., Linnebank, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157544/
https://www.ncbi.nlm.nih.gov/pubmed/25249976
http://dx.doi.org/10.3389/fnagi.2014.00237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157544/
https://www.ncbi.nlm.nih.gov/pubmed/25249976
http://dx.doi.org/10.3389/fnagi.2014.00237

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