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Hepatic Localization of Macrophage Phenotypes during Fibrogenesis and Resolution of Fibrosis in Mice and Humans

Macrophages have been found to both promote liver fibrosis and contribute to its resolution by acquiring different phenotypes based on signals from the micro-environment. The best-characterized phenotypes in the macrophage spectrum are labeled M1 (classically activated) and M2 (alternatively activat...

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Detalles Bibliográficos
Autores principales: Beljaars, Leonie, Schippers, Marlies, Reker-Smit, Catharina, Martinez, Fernando O., Helming, Laura, Poelstra, Klaas, Melgert, Barbro N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157549/
https://www.ncbi.nlm.nih.gov/pubmed/25250030
http://dx.doi.org/10.3389/fimmu.2014.00430