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A Novel Prothrombotic Pathway in Systemic Sclerosis Patients: Possible Role of Bisphosphonate-Activated γδ T Cells

Objectives: Infusions of aminobisphonates (ABP) activate Vγ9δ2T cells in vivo and induce an acute inflammatory response in 30% of patients treated for osteoporosis. Following the observation of digital thrombosis in a systemic sclerosis (SSc) patient after treatment with an intravenous ABP, zoledron...

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Detalles Bibliográficos
Autores principales: Marcu-Malina, Victoria, Balbir-Gurman, Alexandra, Dardik, Rima, Braun-Moscovici, Yolanda, Segel, Michael J., Bank, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157565/
https://www.ncbi.nlm.nih.gov/pubmed/25250025
http://dx.doi.org/10.3389/fimmu.2014.00414