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Promoting endothelial recovery and reducing neointimal hyperplasia using sequential-like release of acetylsalicylic acid and paclitaxel-loaded biodegradable stents

INTRODUCTION: This work reports on the development of a biodegradable dual-drug-eluting stent with sequential-like and sustainable drug-release of anti-platelet acetylsalicylic acid and anti-smooth muscle cell (SMC) proliferative paclitaxel. METHODS: To fabricate the biodegradable stents, poly-L-lac...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Hung, Yu, Chia-Ying, Chang, Shang-Hung, Hung, Kuo-Chun, Liu, Shih-Jung, Wang, Chao-Jan, Hsu, Ming-Yi, Hsieh, I-Chang, Chen, Wei-Jan, Ko, Yu-Shien, Wen, Ming-Shien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157626/
https://www.ncbi.nlm.nih.gov/pubmed/25206303
http://dx.doi.org/10.2147/IJN.S67721