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Expression of IL-33 and its epigenetic regulation in multiple sclerosis

OBJECTIVE: We examined the expression of IL-33 as an indicator of an innate immune response in relapsing remitting MS (RRMS) and controls. We proposed a link between the expression of IL-33 and IL-33 regulated genes to histone deacetylase (HDAC) activity and in particular HDAC3, an enzyme that plays...

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Detalles Bibliográficos
Autores principales: Zhang, Fanglin, Tossberg, John T, Spurlock, Charles F, Yao, Song-Yi, Aune, Thomas M, Sriram, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157667/
https://www.ncbi.nlm.nih.gov/pubmed/25215310
http://dx.doi.org/10.1002/acn3.47