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A Small Library of Synthetic Di-Substituted 1, 4-Naphthoquinones Induces ROS-Mediated Cell Death in Murine Fibroblasts

Synthesis of compound libraries and their concurrent assessment as selective reagents for probing and modulating biological function continues to be an active area of chemical biology. Microwave-assisted solid-phase Dötz benzannulation reactions have been used to inexpensively synthesize 2, 3-disubs...

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Detalles Bibliográficos
Autores principales: Ramirez, Oscar, Motta-Mena, Laura B., Cordova, Amanda, Garza, Kristine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157788/
https://www.ncbi.nlm.nih.gov/pubmed/25197824
http://dx.doi.org/10.1371/journal.pone.0106828