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Association between Decreased Klotho Blood Levels and Organic Growth Hormone Deficiency in Children with Growth Impairment
OBJECTIVE: Klotho is an aging-modulating protein expressed mainly in the kidneys and choroid plexus, which can also be shed, released into the circulation and act as a hormone. Klotho deficient mice are smaller compared to their wild-type counterparts and their somatotropes show marked atrophy and r...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157849/ https://www.ncbi.nlm.nih.gov/pubmed/25198618 http://dx.doi.org/10.1371/journal.pone.0107174 |