Real-Time Analysis of Imatinib- and Dasatinib-Induced Effects on Chronic Myelogenous Leukemia Cell Interaction with Fibronectin

Attachment of stem leukemic cells to the bone marrow extracellular matrix increases their resistance to chemotherapy and contributes to the disease persistence. In chronic myelogenous leukemia (CML), the activity of the fusion BCR-ABL kinase affects adhesion signaling. Using real-time monitoring of...

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Detalles Bibliográficos
Autores principales: Obr, Adam, Röselová, Pavla, Grebeňová, Dana, Kuželová, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157868/
https://www.ncbi.nlm.nih.gov/pubmed/25198091
http://dx.doi.org/10.1371/journal.pone.0107367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157868/
https://www.ncbi.nlm.nih.gov/pubmed/25198091
http://dx.doi.org/10.1371/journal.pone.0107367

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