Cellular, Molecular and Functional Characterisation of YAC Transgenic Mouse Models of Friedreich Ataxia

BACKGROUND: Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder, caused by a GAA repeat expansion mutation within intron 1 of the FXN gene. We have previously established and performed preliminary characterisation of several human FXN yeast artificial chromosome (YAC) trans...

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Detalles Bibliográficos
Autores principales: Anjomani Virmouni, Sara, Sandi, Chiranjeevi, Al-Mahdawi, Sahar, Pook, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157886/
https://www.ncbi.nlm.nih.gov/pubmed/25198290
http://dx.doi.org/10.1371/journal.pone.0107416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157886/
https://www.ncbi.nlm.nih.gov/pubmed/25198290
http://dx.doi.org/10.1371/journal.pone.0107416

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