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Fluid resuscitation therapy in endotoxemic hamsters improves survival and attenuates capillary perfusion deficits and inflammatory responses by a mechanism related to nitric oxide

BACKGROUND: Relative hypovolemia is frequently found in early stages of severe sepsis and septic shock and prompt and aggressive fluid therapy has become standard of care improving tissue perfusion and patient outcome. This paper investigates the role of the nitric oxide pathway on beneficial microc...

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Detalles Bibliográficos
Autores principales: Villela, Nivaldo Ribeiro, dos Santos, Ana Olimpia Maia Teixeira, de Miranda, Marcos Lopes, Bouskela, Eliete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158098/
https://www.ncbi.nlm.nih.gov/pubmed/25151363
http://dx.doi.org/10.1186/s12967-014-0232-z